Stay Smart with the Holiday Inn Express Hotel Indianapolis South Keystone! Our central Indianapolis location and easy Interstate access makes us the perfect choice for your business or pleasure travel needs. A smile and a warm welcome from our staff will be your first impression of our hotel. Relax and enjoy our newly renovated spacious rooms. Located just 3.5 miles south of downtown Indianapolis on Interstate 65 at exit 107, Keystone Avenue. Minutes drive from the University of Indianapolis, Indiana Convention Center, RCA Dome, Circle Center Mall,Indianapolis Motor Speedway, Indianapolis Zoo , Children's Museum and the soon to open Lucas Oil Stadium. Enjoy our warm setting of our Great Room where our exclusive Express Start Breakfast is served daily from 6 AM-10 AM, or relax Monday - Thursday evenings with our hospitality hour from 6 PM-8 PM, serving light snacks and beverages. The Holiday Inn Express, Indianapolis South Keystone is the ideal location for having the access of downtown Indianapolis at your fingertips! This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-Holiday (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.