A convenient address among Rochester, Minnesota hotels.Experience the community named the "Best Small City in America" by Money Magazine, where cosmopolitan atmosphere meets Midwestern hospitality. Located in the heart of this bustling locale, the Holiday Inn Express Hotel Rochester City Centre offers a memorable destination for your next vacation or business conference. Look to our downtown Rochester, Minnesota hotel for direct climate-controlled subway/skyway access to the city's attractions, including the world-famous Mayo Clinic. Explore the shops at the adjacent Shops at University Square. Complimentary use of YMCA swimming, water park, fitness center 5 blocks from our location. Enjoy classic family fun at Silver Lake Park or Graham Arena-both just two miles away. You'll find our deluxe Rochester, Minnesota hotel provides spacious accommodations and convenient services in a comfortable setting. Feel right at home at our Express-style Holiday Inn Rochester, Minnesota Hotel. Well-appointed rooms are just the beginning at our Holiday Inn Express hotel in Rochester, Minnesota. Enjoy the Express Start Breakfast Bar early. And for lunch and dinner, grab a delicious meal at one of numerous area restaurants, conveniently accessible by subway and skyway. Book now our Mayo package rate of $105 per night including parking. You can book this under the package tab on this page. Elevator for the parking ramp is located in the northwest corner of the parking. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-Holiday (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.