Welcome to the Holiday Inn Riverfront hotel, The Holiday Inn is the premier full-service hotel located in St. Joseph, MO, in historic downtown, conveniently located off I-229 just 40 miles north of Kansas City International Airport. The Holiday Inn sits on the historic site of the first Pony Express weigh station responsible for delivering and receiving mail from the California coast. The hotel is in close proximity to major companies such as Hillyard Industries, Nestle Purina, Herzog Industries, Johnson Controls, Heartland Hospital and Triumph Foods and within 15 minutes of any business or tourist attraction. In addition, you can enjoy a visit to St. Joseph®s Pony Express Museum & Jesse James Museum and Missouri Western State University, along with Terrible's River Boat Casino are just minutes from the hotel. The Holiday Inn Riverfront Hotel offers 169 spacious guest rooms designed to meet the needs of the leisure and corporate traveler, and includes state-of-the-art banquet facilities and a Houlihan's Restaurant and Bar on premises.. The hotel in St. Joseph, MO now features a 24-hour business center, an expanded fitness center as well as an indoor pool, whirlpool, and sauna for your relaxation. Make the Holiday Inn Riverfront Hotel your home away from home when you're traveling to the St. Joseph, Missouri area! This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-Holiday (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.