Welcome to the Holiday Inn Express Warrenton! The Holiday Inn Express Warrenton is located on Interstate 70 between St. Louis and Columbia, Missouri, just west of St. Charles. Our hotel has easy access to many of the St. Louis-area attractions. Centrally located to many Warrenton businesses. Local businesses include Coca-Cola, Truesdale Packaging, SAF Holland , Warrenton Copper, Cascade Plastics and Warrenton Oil Company. Area events:. Every Saturday in July and August: Summer Breeze Concert. August 2: All day Music Fest at the Warrren County Fairgrounds.As always, all of our guest can enjoy our new hot breakfast at our Express Start breakfast bar and the world's best tasting cinnamon roll. Hotel features include free local phone calls, complimentary high-speed Internet service, a business center, meeting room, indoor heated pool, hot tub and a 24 hour fitness center. Visit Warrenton, MO and Stay Smart at the Holiday Inn Express. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-Holiday (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.